Cocaine induces the expression of homer 1b/c, homer 3a/b, and hsp 27 proteins in rat cerebellum

The long homer proteins 1b/c, 2a/b, and 3a/b play an important role in postsynaptic neurons by clustering glutamate receptors and by coupling the receptors with various intracellular effectors. Using immunohistochemistry and Western‐blot analysis, this study shows that the expression of the long hom...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 2007-08, Vol.61 (8), p.587-594
Hauptverfasser:	Dietrich, Jean-Bernard, Arpin-Bott, Marie-Pierre, Kao, Dany, Dirrig-Grosch, Sylvie, Aunis, Dominique, Zwiller, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Carrier Proteins - biosynthesis Carrier Proteins - drug effects Cerebellum - drug effects Cerebellum - metabolism Cocaine - pharmacology Dopamine Uptake Inhibitors - pharmacology heat shock proteins Homer Scaffolding Proteins Immunohistochemistry Intracellular Signaling Peptides and Proteins Male Microscopy, Confocal Neuroglia - drug effects Neuroglia - metabolism Neuronal Plasticity - drug effects Neuronal Plasticity - physiology neuroplasticity Protein Isoforms - biosynthesis Protein Isoforms - drug effects Protein-Serine-Threonine Kinases - biosynthesis Protein-Serine-Threonine Kinases - drug effects psychostimulant Purkinje Cells - drug effects Purkinje Cells - metabolism Rats Rats, Wistar Receptors, Metabotropic Glutamate - drug effects Receptors, Metabotropic Glutamate - metabolism scaffolding proteins
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