Tracking the Chiral Recognition of Adsorbed Dipeptides at the Single-Molecule Level
Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D‐Phe‐D‐Phe, L: L‐Phe‐L‐Phe). With STM movies, the chiral‐recognition process of individual adsorbed di‐phenylalanine m...
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Veröffentlicht in: | Angewandte Chemie International Edition 2007-01, Vol.46 (24), p.4492-4495 |
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creator | Lingenfelder, Magalí Tomba, Giulia Costantini, Giovanni Colombi Ciacchi, Lucio De Vita, Alessandro Kern, Klaus |
description | Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D‐Phe‐D‐Phe, L: L‐Phe‐L‐Phe). With STM movies, the chiral‐recognition process of individual adsorbed di‐phenylalanine molecules is followed to illustrate the dynamic induced‐fit mechanism at the single‐molecule level. |
doi_str_mv | 10.1002/anie.200700194 |
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The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D‐Phe‐D‐Phe, L: L‐Phe‐L‐Phe). 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The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D‐Phe‐D‐Phe, L: L‐Phe‐L‐Phe). With STM movies, the chiral‐recognition process of individual adsorbed di‐phenylalanine molecules is followed to illustrate the dynamic induced‐fit mechanism at the single‐molecule level.</description><subject>Adsorption</subject><subject>Binding Sites</subject><subject>chirality</subject><subject>Copper</subject><subject>density functional calculations</subject><subject>Dipeptides - chemistry</subject><subject>Microscopy, Scanning Tunneling</subject><subject>Molecular Conformation</subject><subject>molecular recognition</subject><subject>peptides</subject><subject>Phenylalanine - analogs & derivatives</subject><subject>Phenylalanine - chemistry</subject><subject>scanning probe microscopy</subject><subject>Stereoisomerism</subject><issn>1433-7851</issn><issn>1521-3773</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAURi0E4lFYGVEmthQ7dnyTsZRXRXmIghgtx7kBg5sUO-Xx7wm0Ajame4dzzvARsston1GaHOjaYj-hFChluVghmyxNWMwB-Gr3C85jyFK2QbZCeOr4LKNynWwwEIKDTDbJ5NZr82zrh6h9xGj4aL120Q2a5qG2rW3qqKmiQRkaX2AZHdkZzlpbYoh0-y1MOtNhfNE4NHOH0Rhf0W2TtUq7gDvL2yN3J8e3w7N4fHU6Gg7GsRECRMwKjpjmXOZZUSaUVwaqstIoCjASAUCjRA5JbkBXlRYAgmooZFqW0AkJ75H9RXfmm5c5hlZNbTDonK6xmQcFVNIEeNaB_QVofBOCx0rNvJ1q_6EYVV8zqq8Z1c-MnbC3LM-LKZa_-HK3DsgXwJt1-PFPTg0uR8d_4_HCtaHF9x9X-2clgUOq7i9PlTw5zM6vJ0wB_wSy-I5P</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Lingenfelder, Magalí</creator><creator>Tomba, Giulia</creator><creator>Costantini, Giovanni</creator><creator>Colombi Ciacchi, Lucio</creator><creator>De Vita, Alessandro</creator><creator>Kern, Klaus</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070101</creationdate><title>Tracking the Chiral Recognition of Adsorbed Dipeptides at the Single-Molecule Level</title><author>Lingenfelder, Magalí ; Tomba, Giulia ; Costantini, Giovanni ; Colombi Ciacchi, Lucio ; De Vita, Alessandro ; Kern, Klaus</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4474-1b3ee593698bd203fc7fdfae4b7c6e777ae6e3729c7affa47740a7b65dd7bd223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adsorption</topic><topic>Binding Sites</topic><topic>chirality</topic><topic>Copper</topic><topic>density functional calculations</topic><topic>Dipeptides - chemistry</topic><topic>Microscopy, Scanning Tunneling</topic><topic>Molecular Conformation</topic><topic>molecular recognition</topic><topic>peptides</topic><topic>Phenylalanine - analogs & derivatives</topic><topic>Phenylalanine - chemistry</topic><topic>scanning probe microscopy</topic><topic>Stereoisomerism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lingenfelder, Magalí</creatorcontrib><creatorcontrib>Tomba, Giulia</creatorcontrib><creatorcontrib>Costantini, Giovanni</creatorcontrib><creatorcontrib>Colombi Ciacchi, Lucio</creatorcontrib><creatorcontrib>De Vita, Alessandro</creatorcontrib><creatorcontrib>Kern, Klaus</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Angewandte Chemie International Edition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lingenfelder, Magalí</au><au>Tomba, Giulia</au><au>Costantini, Giovanni</au><au>Colombi Ciacchi, Lucio</au><au>De Vita, Alessandro</au><au>Kern, Klaus</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tracking the Chiral Recognition of Adsorbed Dipeptides at the Single-Molecule Level</atitle><jtitle>Angewandte Chemie International Edition</jtitle><addtitle>Angewandte Chemie International Edition</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>46</volume><issue>24</issue><spage>4492</spage><epage>4495</epage><pages>4492-4495</pages><issn>1433-7851</issn><eissn>1521-3773</eissn><abstract>Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D‐Phe‐D‐Phe, L: L‐Phe‐L‐Phe). With STM movies, the chiral‐recognition process of individual adsorbed di‐phenylalanine molecules is followed to illustrate the dynamic induced‐fit mechanism at the single‐molecule level.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><pmid>17443762</pmid><doi>10.1002/anie.200700194</doi><tpages>4</tpages></addata></record> |
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subjects | Adsorption Binding Sites chirality Copper density functional calculations Dipeptides - chemistry Microscopy, Scanning Tunneling Molecular Conformation molecular recognition peptides Phenylalanine - analogs & derivatives Phenylalanine - chemistry scanning probe microscopy Stereoisomerism |
title | Tracking the Chiral Recognition of Adsorbed Dipeptides at the Single-Molecule Level |
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