Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

Background & Aims: Ghrelin, an endogenous ligand for growth hormone secretagogue receptor, was recently identified in the rat stomach. We examined the effects of the gastric peptide ghrelin on energy balance in association with leptin and vagal nerve activity. Methods: Food intake, oxygen consum...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2001-02, Vol.120 (2), p.337-345
Hauptverfasser:	Asakawa, Akihiro, Inui, Akio, Kaga, Oshihiro, Yuzuriha, Hideki, Nagata, Toshiaki, Ueno, Naohiko, Makino, Susumu, Fujimiya, Mineko, Niijima, Akira, Fujino, Masayuki A., Kasuga, Masato
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Appetite - physiology Biological and medical sciences Blotting, Northern Digestive system Electrophysiology Energy Metabolism - drug effects Energy Metabolism - physiology Feeding Behavior - drug effects Feeding Behavior - physiology Gastric Emptying - drug effects Gastric Emptying - physiology Gene Expression - physiology Ghrelin Hypothalamus - physiology Injections, Intraventricular Interleukin-1 - pharmacology Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mice Mice, Inbred C57BL Mice, Obese Molecular Sequence Data Motilin - chemistry Motilin - genetics Neuropeptide Y - genetics Oxygen Consumption - drug effects Oxygen Consumption - physiology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Peptide Hormones Peptides - chemistry Peptides - genetics Peptides - pharmacology Rats Rats, Wistar Receptors, Gastrointestinal Hormone - genetics Receptors, Neuropeptide - genetics RNA, Messenger - analysis Stomach - innervation Stomach - physiology Vagus Nerve - drug effects Vagus Nerve - physiology
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