Maternal-fetal transfer and amniotic fluid accumulation of lamivudine in human immunodeficiency virus–infected pregnant women

Objective: The purpose of this study was to investigate placental transfer and amniotic fluid concentrations of lamivudine in human immunodeficiency virus–infected women who received the agent during pregnancy. Study Design: Mothers in the study were receiving antiretroviral therapy that included la...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2001-01, Vol.184 (2), p.153-158
Hauptverfasser:	Mandelbrot, Laurent, Peytavin, Gilles, Firtion, Ghislaine, Farinotti, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - drug therapy Adult Amniotic Fluid - metabolism Amniotic fluid accumulation Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Biological and medical sciences Diffusion Female Fetal Blood - metabolism General pharmacology Humans Kinetics lamivudine Lamivudine - blood Lamivudine - pharmacokinetics Lamivudine - therapeutic use Maternal-Fetal Exchange Medical sciences Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments placental transfer Pregnancy Pregnancy Complications, Infectious - virology safety
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