Free Radical Production by Antibiotic-Killed Bacteria in the Guinea Pig Middle Ear

Objectives Oxygen free radicals are implicated in the pathogenesis of otitis media. Recent investigations with animal models have demonstrated that free radical–mediated damage of the middle ear mucosa, measured as lipid hydroperoxide, occurs when the middle ear cavity is inoculated with Streptococc...

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Veröffentlicht in:	The Laryngoscope 2001-02, Vol.111 (2), p.283-289
Hauptverfasser:	Takoudes, Thomas G., Haddad Jr, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Amoxicillin - pharmacology Animals Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial diseases Biological and medical sciences Ear, Middle - pathology Experimental bacterial diseases and models Free Radicals Guinea Pigs Infectious diseases Lipid Peroxides - metabolism Medical sciences Mucous Membrane - pathology otitis media Otitis Media - pathology Pharmacology. Drug treatments Pneumococcal Infections - pathology pneumococcus Streptococcus pneumoniae - drug effects
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