Computed direct magnification radiography of bone tumors
The purpose of this study was to assess the diagnostic performance of computed direct magnification radiography in diagnosing bone tumors as compared with conventional radiography. Ninety-one patients with primary bone tumors and tumor-like lesions were radiographed with conventional and magnificati...
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| Veröffentlicht in: | Journal of cancer research and clinical oncology 2001-02, Vol.127 (2), p.116-122 |
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| container_title | Journal of cancer research and clinical oncology |
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| creator | HILLMANN, Axel LINK, Thomas Mark OZAKI, Toshifumi VESTRING, Thomas WINKELMANN, Winfried |
| description | The purpose of this study was to assess the diagnostic performance of computed direct magnification radiography in diagnosing bone tumors as compared with conventional radiography. Ninety-one patients with primary bone tumors and tumor-like lesions were radiographed with conventional and magnification techniques. All radiographs were analyzed by one orthopedic surgeon and two radiologists and the findings were correlated with histopathology. Two microfocal X-ray units were used for computed direct magnification radiography with a focal spot size of 20-130 microm. Using magnification versus conventional radiography, the diagnosis of benign and malignant lesions as well as the individual tumor diagnosis was obtained with higher accuracy (85% versus 71% and 69% versus 51%, respectively, P |
| doi_str_mv | 10.1007/s004320000179 |
| format | Article |
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Ninety-one patients with primary bone tumors and tumor-like lesions were radiographed with conventional and magnification techniques. All radiographs were analyzed by one orthopedic surgeon and two radiologists and the findings were correlated with histopathology. Two microfocal X-ray units were used for computed direct magnification radiography with a focal spot size of 20-130 microm. Using magnification versus conventional radiography, the diagnosis of benign and malignant lesions as well as the individual tumor diagnosis was obtained with higher accuracy (85% versus 71% and 69% versus 51%, respectively, P<0.01). Margins of destruction, periosteal reactions, and matrix patterns were evaluated with higher accuracy by all observers (P<0.01). We conclude that computed direct magnification radiography may improve evaluation and diagnosis of bone tumors.</description><identifier>ISSN: 0171-5216</identifier><identifier>EISSN: 1432-1335</identifier><identifier>DOI: 10.1007/s004320000179</identifier><identifier>PMID: 11216912</identifier><identifier>CODEN: JCROD7</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; Biological and medical sciences ; Bone Diseases - diagnostic imaging ; Bone Neoplasms - diagnostic imaging ; Diagnosis, Differential ; Diseases of the osteoarticular system ; Humans ; Medical sciences ; Observer Variation ; Predictive Value of Tests ; Prospective Studies ; Radiographic Image Enhancement - methods ; Tumors of striated muscle and skeleton</subject><ispartof>Journal of cancer research and clinical oncology, 2001-02, Vol.127 (2), p.116-122</ispartof><rights>2001 INIST-CNRS</rights><rights>Springer-Verlag Berlin Heidelberg 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-17ff375bb610292b55e2bbb3f9c46f300d9a0364c249817dcf51bf09ce2b2d543</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=938257$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11216912$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HILLMANN, Axel</creatorcontrib><creatorcontrib>LINK, Thomas Mark</creatorcontrib><creatorcontrib>OZAKI, Toshifumi</creatorcontrib><creatorcontrib>VESTRING, Thomas</creatorcontrib><creatorcontrib>WINKELMANN, Winfried</creatorcontrib><title>Computed direct magnification radiography of bone tumors</title><title>Journal of cancer research and clinical oncology</title><addtitle>J Cancer Res Clin Oncol</addtitle><description>The purpose of this study was to assess the diagnostic performance of computed direct magnification radiography in diagnosing bone tumors as compared with conventional radiography. Ninety-one patients with primary bone tumors and tumor-like lesions were radiographed with conventional and magnification techniques. All radiographs were analyzed by one orthopedic surgeon and two radiologists and the findings were correlated with histopathology. Two microfocal X-ray units were used for computed direct magnification radiography with a focal spot size of 20-130 microm. Using magnification versus conventional radiography, the diagnosis of benign and malignant lesions as well as the individual tumor diagnosis was obtained with higher accuracy (85% versus 71% and 69% versus 51%, respectively, P<0.01). Margins of destruction, periosteal reactions, and matrix patterns were evaluated with higher accuracy by all observers (P<0.01). We conclude that computed direct magnification radiography may improve evaluation and diagnosis of bone tumors.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Bone Diseases - diagnostic imaging</subject><subject>Bone Neoplasms - diagnostic imaging</subject><subject>Diagnosis, Differential</subject><subject>Diseases of the osteoarticular system</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Observer Variation</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Radiographic Image Enhancement - methods</subject><subject>Tumors of striated muscle and skeleton</subject><issn>0171-5216</issn><issn>1432-1335</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpd0E1LxDAQBuAgiruuHr1KUfBWzeSj2Rxl8QsWvOi5JGmydmmbmrSH_fdm2aLoXIYZHobhRegS8B1gLO4jxowSnAqEPEJzSFMOlPJjNE8ryDmBYobOYtzuCRfkFM0A0lICmaPlyrf9ONgqq-pgzZC1atPVrjZqqH2XBVXVfhNU_7nLvMu072w2jK0P8RydONVEezH1Bfp4enxfveTrt-fX1cM6N5SxIQfhHBVc6wIwkURzbonWmjppWOEoxpVUmBbMECaXICrjOGiHpUmMVJzRBbo93O2D_xptHMq2jsY2jeqsH2MpMF9KwnCC1__g1o-hS7-VkgDjwGSRUH5AJvgYg3VlH-pWhV0JuNznWf7JM_mr6eioW1v96inABG4moKJRjQuqM3X8cZIuCRf0G9yeers</recordid><startdate>20010201</startdate><enddate>20010201</enddate><creator>HILLMANN, Axel</creator><creator>LINK, Thomas Mark</creator><creator>OZAKI, Toshifumi</creator><creator>VESTRING, Thomas</creator><creator>WINKELMANN, Winfried</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20010201</creationdate><title>Computed direct magnification radiography of bone tumors</title><author>HILLMANN, Axel ; LINK, Thomas Mark ; OZAKI, Toshifumi ; VESTRING, Thomas ; WINKELMANN, Winfried</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-17ff375bb610292b55e2bbb3f9c46f300d9a0364c249817dcf51bf09ce2b2d543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Bone Diseases - diagnostic imaging</topic><topic>Bone Neoplasms - diagnostic imaging</topic><topic>Diagnosis, Differential</topic><topic>Diseases of the osteoarticular system</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Observer Variation</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Radiographic Image Enhancement - methods</topic><topic>Tumors of striated muscle and skeleton</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HILLMANN, Axel</creatorcontrib><creatorcontrib>LINK, Thomas Mark</creatorcontrib><creatorcontrib>OZAKI, Toshifumi</creatorcontrib><creatorcontrib>VESTRING, Thomas</creatorcontrib><creatorcontrib>WINKELMANN, Winfried</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cancer research and clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HILLMANN, Axel</au><au>LINK, Thomas Mark</au><au>OZAKI, Toshifumi</au><au>VESTRING, Thomas</au><au>WINKELMANN, Winfried</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computed direct magnification radiography of bone tumors</atitle><jtitle>Journal of cancer research and clinical oncology</jtitle><addtitle>J Cancer Res Clin Oncol</addtitle><date>2001-02-01</date><risdate>2001</risdate><volume>127</volume><issue>2</issue><spage>116</spage><epage>122</epage><pages>116-122</pages><issn>0171-5216</issn><eissn>1432-1335</eissn><coden>JCROD7</coden><abstract>The purpose of this study was to assess the diagnostic performance of computed direct magnification radiography in diagnosing bone tumors as compared with conventional radiography. Ninety-one patients with primary bone tumors and tumor-like lesions were radiographed with conventional and magnification techniques. All radiographs were analyzed by one orthopedic surgeon and two radiologists and the findings were correlated with histopathology. Two microfocal X-ray units were used for computed direct magnification radiography with a focal spot size of 20-130 microm. Using magnification versus conventional radiography, the diagnosis of benign and malignant lesions as well as the individual tumor diagnosis was obtained with higher accuracy (85% versus 71% and 69% versus 51%, respectively, P<0.01). Margins of destruction, periosteal reactions, and matrix patterns were evaluated with higher accuracy by all observers (P<0.01). We conclude that computed direct magnification radiography may improve evaluation and diagnosis of bone tumors.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>11216912</pmid><doi>10.1007/s004320000179</doi><tpages>7</tpages></addata></record> |
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| subjects | Adult Biological and medical sciences Bone Diseases - diagnostic imaging Bone Neoplasms - diagnostic imaging Diagnosis, Differential Diseases of the osteoarticular system Humans Medical sciences Observer Variation Predictive Value of Tests Prospective Studies Radiographic Image Enhancement - methods Tumors of striated muscle and skeleton |
| title | Computed direct magnification radiography of bone tumors |
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