A Novel Cell Culture Model of Chondrocyte Differentiation During Mammalian Endochondral Ossification

Endochondral ossification (EO) occurs in the growth plate where chondrocytes pass through discrete stages of proliferation, maturation, hypertrophy, and calcification. We have developed and characterized a novel bovine cell culture model of EO that mirrors these events and will facilitate in vitro s...

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Veröffentlicht in:	Journal of bone and mineral research 2001-02, Vol.16 (2), p.309-318
Hauptverfasser:	Cheung, J. O. P., Hillarby, M. C., Ayad, S., Hoyland, J. A., Jones, C. J. P., Denton, J., Thomas, J. T., Wallis, G. A., Grant, M. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Azacytidine Animal cells Animals Azacitidine - pharmacology azacytidine Base Sequence Biological and medical sciences Bone and Bones - embryology Calcification, Physiologic Cattle cell culture Cell cultures. Hybridization. Fusion Cells, Cultured chondrocyte Chondrocytes - cytology Chondrocytes - drug effects DNA Primers endochondral ossification Fundamental and applied biological sciences. Psychology growth plate Immunohistochemistry Models, Biological Molecular and cellular biology Parathyroid Hormone-Related Protein Phenotype Proteins - pharmacology Skeleton and joints Vertebrates: osteoarticular system, musculoskeletal system
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