Suppression of hepatitis B virus replication mediated by hepatitis A-induced cytokine production

: Background: Acute hepatitis A virus (HAV) infection can cause severe hepatitis especially in patients with underlying chronic liver disease. In patients with pre‐existing chronic hepatitis B (HBV) acute HAV infection can suppress HBV replication. The exact mechanism of HBV suppression during acute...

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Veröffentlicht in:	Liver (Copenhagen) 2001-02, Vol.21 (1), p.45-49
Hauptverfasser:	Van Nunen, Andeltje B., Pontesilli, Oscar, Uytdehaag, Fons, Osterhaus, Albert D. M. E., De Man, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute hepatitis A alpha interferon Antiviral Agents - therapeutic use Biological and medical sciences Cells, Cultured chronic hepatitis B DNA, Viral - analysis gamma-interferon Hepatitis A - blood Hepatitis A - immunology Hepatitis B Core Antigens - blood Hepatitis B virus - genetics Hepatitis B virus - growth & development Hepatitis B virus - immunology Hepatitis B virus - isolation & purification Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - immunology Hepatovirus - immunology Hepatovirus - isolation & purification Human viral diseases Humans IL-10 IL-12 Infectious diseases Interferon-gamma - biosynthesis Lamivudine - therapeutic use lympho-proliferative response Lymphocyte Activation - immunology Male Medical sciences Superinfection - immunology TNF-alpha Viral diseases Viral hepatitis Viral Interference - immunology Virus Replication
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