Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers
The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental...
Gespeichert in:
| Veröffentlicht in: | Pharmacology, biochemistry and behavior biochemistry and behavior, 2007-04, Vol.86 (4), p.758-765 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 765 |
|---|---|
| container_issue | 4 |
| container_start_page | 758 |
| container_title | Pharmacology, biochemistry and behavior |
| container_volume | 86 |
| creator | Neumann, David L. Fitzgerald, Zoë T. Furedy, John J. Boyle, Gregory J. |
| description | The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental rotation tasks while concurrent psychophysiological recordings were taken. Nicotine administration showed a sexually dimorphic effect on arousal (skin conductance level and heart rate). Evidence of superior performance in males compared to females was found in reaction time and accuracy measures for the visual-spatial tasks. However, performance reflected the interaction between sex and nicotine. Nicotine slowed reaction times in the mental rotation tasks more extensively in females than males. Nicotine also reduced confidence in performance during the water-level task in males, but not in females. The effects of nicotine on visual-spatial ability may reflect the interactive effects of sex and changes in arousal levels induced by nicotine administration. |
| doi_str_mv | 10.1016/j.pbb.2007.03.001 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70585864</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0091305707000949</els_id><sourcerecordid>20621926</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-5a761a840ccc2c0fed749e0578873f20c6c7875012528ac289120930fc4c71143</originalsourceid><addsrcrecordid>eNqFkc2KFDEUhYM4OO3oA7iRbHRXNTepn6RwJcP4AwOzUNchfeuWk7YqKZOqZnrpm5umG2anEAgk3z3k5GPsjYBSgGivd-W83ZYSQJVQlQDiGdsIraqiEUo9ZxuAThQVNOqSvUxpBwC1bNULdilUDUp1sGF_vtHjasfxwHs3hTg_OOQ0DIRL4mHgFteFuHcYFueJ235y3qUl2sUFz_OyMazJjtz6nu9dylFFmvPt8WjrRrccuPPcB1-kKfxy_id_WCfr-T6Mq1-IYnrFLgY7Jnp93q_Yj0-332--FHf3n7_efLwrsG6apWisaoXVNSCiRBioV3VHuZvOhQcJ2KLSqgEhG6ktSt0JCV0FA9aohKirK_b-lDvH8HultJjJJaRxtJ5yB6Og0Y1u_w9KaKXoZJtBcQIxhpQiDWaObrLxYASYoyCzM1mQOQoyUJksKM-8PYev24n6p4mzkQy8OwM2oR2HaD269MRpLVvZdpn7cOIo_9neUTQJHXmk3sVsz_TB_eMZfwFfVK9P</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20621926</pqid></control><display><type>article</type><title>Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Neumann, David L. ; Fitzgerald, Zoë T. ; Furedy, John J. ; Boyle, Gregory J.</creator><creatorcontrib>Neumann, David L. ; Fitzgerald, Zoë T. ; Furedy, John J. ; Boyle, Gregory J.</creatorcontrib><description>The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental rotation tasks while concurrent psychophysiological recordings were taken. Nicotine administration showed a sexually dimorphic effect on arousal (skin conductance level and heart rate). Evidence of superior performance in males compared to females was found in reaction time and accuracy measures for the visual-spatial tasks. However, performance reflected the interaction between sex and nicotine. Nicotine slowed reaction times in the mental rotation tasks more extensively in females than males. Nicotine also reduced confidence in performance during the water-level task in males, but not in females. The effects of nicotine on visual-spatial ability may reflect the interactive effects of sex and changes in arousal levels induced by nicotine administration.</description><identifier>ISSN: 0091-3057</identifier><identifier>EISSN: 1873-5177</identifier><identifier>DOI: 10.1016/j.pbb.2007.03.001</identifier><identifier>PMID: 17407790</identifier><identifier>CODEN: PBBHAU</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Addictive behaviors ; Adolescent ; Adult ; Adult and adolescent clinical studies ; Arousal ; Arousal - drug effects ; Biological and medical sciences ; Female ; Heart rate ; Humans ; Male ; Medical sciences ; Nicotine ; Nicotine - administration & dosage ; Psychology. Psychoanalysis. Psychiatry ; Psychomotor Performance - drug effects ; Psychopathology. Psychiatry ; Psychophysiology ; Sex Characteristics ; Skin conductance ; Tobacco smoking ; Tobacco, tobacco smoking ; Toxicology ; Visual-spatial ability</subject><ispartof>Pharmacology, biochemistry and behavior, 2007-04, Vol.86 (4), p.758-765</ispartof><rights>2007 Elsevier Inc.</rights><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-5a761a840ccc2c0fed749e0578873f20c6c7875012528ac289120930fc4c71143</citedby><cites>FETCH-LOGICAL-c455t-5a761a840ccc2c0fed749e0578873f20c6c7875012528ac289120930fc4c71143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.pbb.2007.03.001$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18826269$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17407790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Neumann, David L.</creatorcontrib><creatorcontrib>Fitzgerald, Zoë T.</creatorcontrib><creatorcontrib>Furedy, John J.</creatorcontrib><creatorcontrib>Boyle, Gregory J.</creatorcontrib><title>Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers</title><title>Pharmacology, biochemistry and behavior</title><addtitle>Pharmacol Biochem Behav</addtitle><description>The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental rotation tasks while concurrent psychophysiological recordings were taken. Nicotine administration showed a sexually dimorphic effect on arousal (skin conductance level and heart rate). Evidence of superior performance in males compared to females was found in reaction time and accuracy measures for the visual-spatial tasks. However, performance reflected the interaction between sex and nicotine. Nicotine slowed reaction times in the mental rotation tasks more extensively in females than males. Nicotine also reduced confidence in performance during the water-level task in males, but not in females. The effects of nicotine on visual-spatial ability may reflect the interactive effects of sex and changes in arousal levels induced by nicotine administration.</description><subject>Addictive behaviors</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Arousal</subject><subject>Arousal - drug effects</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Heart rate</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nicotine</subject><subject>Nicotine - administration & dosage</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychomotor Performance - drug effects</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychophysiology</subject><subject>Sex Characteristics</subject><subject>Skin conductance</subject><subject>Tobacco smoking</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><subject>Visual-spatial ability</subject><issn>0091-3057</issn><issn>1873-5177</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc2KFDEUhYM4OO3oA7iRbHRXNTepn6RwJcP4AwOzUNchfeuWk7YqKZOqZnrpm5umG2anEAgk3z3k5GPsjYBSgGivd-W83ZYSQJVQlQDiGdsIraqiEUo9ZxuAThQVNOqSvUxpBwC1bNULdilUDUp1sGF_vtHjasfxwHs3hTg_OOQ0DIRL4mHgFteFuHcYFueJ235y3qUl2sUFz_OyMazJjtz6nu9dylFFmvPt8WjrRrccuPPcB1-kKfxy_id_WCfr-T6Mq1-IYnrFLgY7Jnp93q_Yj0-332--FHf3n7_efLwrsG6apWisaoXVNSCiRBioV3VHuZvOhQcJ2KLSqgEhG6ktSt0JCV0FA9aohKirK_b-lDvH8HultJjJJaRxtJ5yB6Og0Y1u_w9KaKXoZJtBcQIxhpQiDWaObrLxYASYoyCzM1mQOQoyUJksKM-8PYev24n6p4mzkQy8OwM2oR2HaD269MRpLVvZdpn7cOIo_9neUTQJHXmk3sVsz_TB_eMZfwFfVK9P</recordid><startdate>20070401</startdate><enddate>20070401</enddate><creator>Neumann, David L.</creator><creator>Fitzgerald, Zoë T.</creator><creator>Furedy, John J.</creator><creator>Boyle, Gregory J.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20070401</creationdate><title>Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers</title><author>Neumann, David L. ; Fitzgerald, Zoë T. ; Furedy, John J. ; Boyle, Gregory J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-5a761a840ccc2c0fed749e0578873f20c6c7875012528ac289120930fc4c71143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Addictive behaviors</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Arousal</topic><topic>Arousal - drug effects</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Heart rate</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nicotine</topic><topic>Nicotine - administration & dosage</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychomotor Performance - drug effects</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychophysiology</topic><topic>Sex Characteristics</topic><topic>Skin conductance</topic><topic>Tobacco smoking</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><topic>Visual-spatial ability</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Neumann, David L.</creatorcontrib><creatorcontrib>Fitzgerald, Zoë T.</creatorcontrib><creatorcontrib>Furedy, John J.</creatorcontrib><creatorcontrib>Boyle, Gregory J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacology, biochemistry and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Neumann, David L.</au><au>Fitzgerald, Zoë T.</au><au>Furedy, John J.</au><au>Boyle, Gregory J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers</atitle><jtitle>Pharmacology, biochemistry and behavior</jtitle><addtitle>Pharmacol Biochem Behav</addtitle><date>2007-04-01</date><risdate>2007</risdate><volume>86</volume><issue>4</issue><spage>758</spage><epage>765</epage><pages>758-765</pages><issn>0091-3057</issn><eissn>1873-5177</eissn><coden>PBBHAU</coden><abstract>The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental rotation tasks while concurrent psychophysiological recordings were taken. Nicotine administration showed a sexually dimorphic effect on arousal (skin conductance level and heart rate). Evidence of superior performance in males compared to females was found in reaction time and accuracy measures for the visual-spatial tasks. However, performance reflected the interaction between sex and nicotine. Nicotine slowed reaction times in the mental rotation tasks more extensively in females than males. Nicotine also reduced confidence in performance during the water-level task in males, but not in females. The effects of nicotine on visual-spatial ability may reflect the interactive effects of sex and changes in arousal levels induced by nicotine administration.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17407790</pmid><doi>10.1016/j.pbb.2007.03.001</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0091-3057 |
| ispartof | Pharmacology, biochemistry and behavior, 2007-04, Vol.86 (4), p.758-765 |
| issn | 0091-3057 1873-5177 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70585864 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Addictive behaviors Adolescent Adult Adult and adolescent clinical studies Arousal Arousal - drug effects Biological and medical sciences Female Heart rate Humans Male Medical sciences Nicotine Nicotine - administration & dosage Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - drug effects Psychopathology. Psychiatry Psychophysiology Sex Characteristics Skin conductance Tobacco smoking Tobacco, tobacco smoking Toxicology Visual-spatial ability |
| title | Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T02%3A25%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sexually%20dimorphic%20effects%20of%20acute%20nicotine%20administration%20on%20arousal%20and%20visual-spatial%20ability%20in%20non-smoking%20human%20volunteers&rft.jtitle=Pharmacology,%20biochemistry%20and%20behavior&rft.au=Neumann,%20David%20L.&rft.date=2007-04-01&rft.volume=86&rft.issue=4&rft.spage=758&rft.epage=765&rft.pages=758-765&rft.issn=0091-3057&rft.eissn=1873-5177&rft.coden=PBBHAU&rft_id=info:doi/10.1016/j.pbb.2007.03.001&rft_dat=%3Cproquest_cross%3E20621926%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=20621926&rft_id=info:pmid/17407790&rft_els_id=S0091305707000949&rfr_iscdi=true |