A method for measuring potency of narasin extracts using near-IR spectroscopy

We present a method for extracting the active component from granulated narasin samples using chloroform with subsequent quantitation by near-infrared absorption spectroscopy (NIRS). A multiple linear regression (MLR) calibration equation was developed using a set of 41 calibration samples. The pote...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2001, Vol.24 (3), p.437-451
Hauptverfasser:	Morris, Daniel L, Forbes, Robert A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical method validation Biological and medical sciences Calibration Chemometrics General pharmacology Ionophore Medical sciences Multiple linear regression (MLR) Narasin Pharmaceutical analysis Pharmacology. Drug treatments Pyrans - analysis Pyrans - pharmacology Reproducibility of Results Sensitivity and Specificity Solvents Spectroscopy, Near-Infrared - methods Transmission near infrared (NIR) spectroscopy
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