$Two‐year effects of alendronate on bone mineral density and vertebral fracture in patients receiving glucocorticoids: A randomized, double‐blind, placebo‐controlled extension trial$

Two‐year effects of alendronate on bone mineral density and vertebral fracture in patients receiving glucocorticoids: A randomized, double‐blind, placebo‐controlled extension trial

Objective To evaluate the continued efficacy and safety of alendronate (ALN) for up to 2 years in patients receiving glucocorticoids. Methods This is a 12‐month extension of a previously completed 1‐year trial of daily ALN, performed to evaluate the effects of ALN over a total of 2 years in 66 men a...

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Veröffentlicht in:	Arthritis and rheumatism 2001-01, Vol.44 (1), p.202-211
Hauptverfasser:	Adachi, Jonathan D., Saag, Kenneth G., Delmas, Pierre D., Liberman, Uri A., Emkey, Ronald D., Seeman, Ego, Lane, Nancy E., Kaufman, Jean‐Marc, Poubelle, Patrice E. E., Hawkins, Federico, Correa‐Rotter, Ricardo, Menkes, Charles‐Joel, Rodriguez‐Portales, Jose A., Schnitzer, Thomas J., Block, Joel A., Wing, Jeffrey, McIlwain, Harris H., Westhovens, Rene, Brown, Jacques, Melo‐Gomes, Jose A., Gruber, Barry L., Yanover, Melissa J., Leite, Maria Odette R., Siminoski, Kerry G., Nevitt, Michael C., Sharp, John T., Malice, Marie‐Pierre, Dumortier, Thomas, Czachur, Michelle, Carofano, Wendy, Daifotis, Anastasia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alendronate - pharmacology Arthrography Biological and medical sciences Bone Density - drug effects Bone Resorption - diagnosis Double-Blind Method Drug toxicity and drugs side effects treatment Female Glucocorticoids - therapeutic use Humans Joints - pathology Male Medical sciences Middle Aged Pharmacology. Drug treatments Placebos - pharmacology Spinal Fractures - drug therapy Spinal Fractures - prevention & control Time Factors Toxicity: osteoarticular system
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