A novel approach for the determination of contractile and calcium responses of the basilar artery employing real-time confocal laser microscopy

Intracellular calcium concentration ([Ca 2+] i) modifications in endothelial and smooth muscle cells represent a key element in the pathogenesis of cerebral artery vasospasm. Therefore, the present study documented potential application of confocal laser microscopy in the determination of contractil...

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Veröffentlicht in:	Journal of pharmacological and toxicological methods 2007-07, Vol.56 (1), p.79-86
Hauptverfasser:	Hashimoto, Terumasa, Ohata, Hisayuki, Nobe, Koji, Sakai, Yasushi, Honda, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Animals Basilar artery Basilar Artery - drug effects Basilar Artery - physiology Calcium - metabolism Confocal microscopy Contraction Dose-Response Relationship, Drug In Vitro Techniques Intracellular calcium Intracellular Fluid - metabolism Male Microscopy, Confocal Muscle Contraction Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Periodicity Rat Rats Rats, Wistar Serotonin - pharmacology Vasopressins - pharmacology
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