The impact of hypercarbia on the evolution of brain injury in a porcine model of traumatic brain injury and systemic hemorrhage

Carbon dioxide is perhaps the most potent available modulator of cerebrovascular tone and thus cerebral blood flow (CBF). These experiments evaluate the impact of induced hypercarbia on the matching of blood flow and metabolism in the injured brain. We explore the hypothesis that hypercarbia will re...

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Veröffentlicht in:	Journal of neurotrauma 2001, Vol.18 (1), p.57-71
Hauptverfasser:	GLASS, Todd F, FABIAN, Matthew J, SCHWEITZER, John B, WEINBERG, Joseph A, PROCTOR, Kenneth G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Axons - pathology Biological and medical sciences Blood Pressure - physiology Brain - metabolism Brain - pathology Brain - physiopathology Brain Injuries - metabolism Brain Injuries - pathology Brain Injuries - physiopathology Brain Ischemia - metabolism Brain Ischemia - physiopathology Carbon dioxide Carbon Dioxide - metabolism Cardiac Output - physiology Cerebrovascular Circulation - physiology Disease Models, Animal Disease Progression Emergency and intensive care: injuries, diseases due to physical agents. Diving. Drowning. Disaster medicine Evolution Female Glasgow Coma Scale - statistics & numerical data Glucose Glucose - metabolism Hemorrhage Hemorrhage - metabolism Hemorrhage - physiopathology Hydrogen-Ion Concentration Hyperventilation Hypotension Hypotheses Intensive care medicine Intracranial Pressure - physiology Ischemia Lactic Acid - metabolism Male Medical sciences Metabolism Metabolites Oxygen Consumption - physiology Pediatrics Swine Trauma Traumatic brain injury
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