Pse1/Kap121‐dependent nuclear localization of the major yeast multidrug resistance (MDR) transcription factor Pdr1

Pdr1 and Pdr3 are two very similar transcription factors that mainly control membrane biogenesis by adjusting the production of different membrane proteins, such as different ABC or major facilitator superfamily (MFS) transporters. We observed that the pse1‐1 mutation in the importin/β‐karyopherin P...

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Veröffentlicht in:	Molecular microbiology 2001-01, Vol.39 (2), p.304-313
Hauptverfasser:	Delahodde, Agnès, Pandjaitan, Rudy, Corral‐Debrinski, Marisol, Jacq, Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antifungal Agents - pharmacology Ascomycetes Cell Nucleus - metabolism Cycloheximide - pharmacology DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drug Resistance, Microbial - genetics Drug Resistance, Multiple - genetics Fungal Proteins - genetics Fungal Proteins - metabolism Gene Expression Regulation, Fungal Green Fluorescent Proteins Kap121 protein Luminescent Proteins - genetics Luminescent Proteins - metabolism Membrane Transport Proteins Molecular Sequence Data Nuclear Localization Signals - genetics Nuclear Localization Signals - metabolism Pdr1 protein Pdr3 protein Pho4 protein Plasmids - genetics Pse1 protein Receptors, Cytoplasmic and Nuclear - genetics Receptors, Cytoplasmic and Nuclear - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Saccharomyces cerevisiae Proteins Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors Yeasts - drug effects Yeasts - genetics Yeasts - metabolism
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