Simultaneous Multiorgan Presence of Human Herpesvirus 8 and Restricted Lymphotropism of Epstein-Barr Virus DNA Sequences in a Human Immunodeficiency Virus—Negative Immunodeficient Infant

Because a profound dysregulation of the immune system occurs in primary immunodeficiencies, viral infections are not uncommon. Human herpesvirus (HHV)-8 DNA was detected by polymerase chain reaction (PCR) analysis, Southern blotting, and in situ hybridization (ISH) in peripheral blood mononuclear ce...

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Veröffentlicht in:	The Journal of infectious diseases 2001-01, Vol.183 (2), p.338-342
Hauptverfasser:	Sánchez-Velasco, Pablo, Ocejo-Vinyals, Javier G., Flores, Reyes, Gómez-Román, José J., Lozano, María-José, Leyva-Cobián, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents B lymphocytes Biological and medical sciences Blotting, Southern Cell lines Concise Communications DiGeorge Syndrome - complications DNA, Viral - analysis DNA, Viral - genetics Endothelial cells Endothelium - cytology Endothelium - virology Epithelial cells Epithelial Cells - virology Epstein Barr virus infections Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - virology Female Hepatic stellate cells Herpesviridae Infections - complications Herpesviridae Infections - virology Herpesvirus Herpesvirus 4, Human - genetics Herpesvirus 4, Human - isolation & purification Herpesvirus 8, Human - genetics Herpesvirus 8, Human - isolation & purification HIV Seronegativity Human herpesvirus 8 Human viral diseases Humans In Situ Hybridization Infant, Newborn Infectious diseases Kupffer cells Leukocytes, Mononuclear - virology Lymphoid Tissue - virology Macrophages - virology Medical sciences Nucleotide sequences Opportunistic Infections - complications Opportunistic Infections - virology Pharmacology. Drug treatments Polymerase Chain Reaction Sequence Analysis, DNA Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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