α-Synuclein-positive structures in cases with sporadic Alzheimer’s disease: morphology and its relationship to tau aggregation

Alzheimer’s disease (AD) and Parkinson’s disease share common clinical and pathological features. In this study, we examined the relationship between AD pathology and α-synuclein aggregation. The frequency and distribution of α-synuclein-positive structures were systematically investigated in 27 cas...

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Veröffentlicht in:	Brain research 2001-01, Vol.888 (2), p.287-296
Hauptverfasser:	Arai, Yasushi, Yamazaki, Mineo, Mori, Osamu, Muramatsu, Hiromi, Asano, Goro, Katayama, Yasuo
Format:	Artikel
Sprache:	eng
Schlagworte:	a-Synuclein Aged Aged, 80 and over alpha-Synuclein Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer’s disease Biological and medical sciences Brain - metabolism Brain - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia with Lewy bodies Female Humans Immunohistochemistry Inclusion Bodies - metabolism Inclusion Bodies - pathology Lewy bodies Male Medical sciences Microscopy, Confocal Middle Aged Nerve Tissue Proteins - metabolism Neurites - metabolism Neurites - pathology Neurofibrillary Tangles - pathology Neurology Plaque, Amyloid - pathology Synucleins tau Proteins - metabolism α-Synuclein
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