Persistent Depots of Influenza Antigen Fail To Induce a Cytotoxic CD8 T Cell Response

Encounter with Ag during chronic infections results in the generation of phenotypically and functionally heterogeneous subsets of Ag-specific CD8 T cells. Influenza, an acute infection, results in the generation of similar CD8 T cell heterogeneity, which may be attributed to long-lived depots of flu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of Immunology 2007-06, Vol.178 (12), p.7563-7570
Hauptverfasser:	Jelley-Gibbs, Dawn M, Dibble, John P, Brown, Deborah M, Strutt, Tara M, McKinstry, K. Kai, Swain, Susan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Antigens, Viral - immunology Humans Influenza, Human - immunology Lung - immunology Lymphocyte Activation Mice Mice, Transgenic Receptors, Antigen, T-Cell - genetics T-Lymphocyte Subsets - immunology T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!