Differential neuroimmune markers to the onset of Alzheimer's disease neurodegeneration and dementia: autoantibodies to Abeta((25-35)) oligomers, S100b and neurotransmitters

Alzheimer's disease (AD) autoimmunity is a focus for dementia prevention. Generated autoantibodies against major etiopathogenic molecular targets as neuroimmune markers of dementia were measured by ELISA in patient sera. Biphasic antibody levels to Abeta((25-35)) oligomers, S100b and DA were de...

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Veröffentlicht in:	Journal of neuroimmunology 2007-05, Vol.186 (1-2), p.181-192
Hauptverfasser:	Gruden, Marina A, Davidova, Tatyana B, Malisauskas, Mantas, Sewell, Robert D E, Voskresenskaya, Nina I, Wilhelm, Kristina, Elistratova, Elena I, Sherstnev, Vladimir V, Morozova-Roche, Ludmilla A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - complications Alzheimer Disease - immunology Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyloid beta-Peptides - immunology Antibodies - metabolism Cognition Disorders - etiology Dopamine Enzyme-Linked Immunosorbent Assay - methods Female Humans Longitudinal Studies Magnetic Resonance Imaging - methods Nerve Degeneration - immunology Nerve Degeneration - metabolism Nerve Degeneration - pathology Nerve Growth Factors - immunology Peptide Fragments - immunology Peptide Fragments - metabolism S100 Calcium Binding Protein beta Subunit S100 Proteins - immunology Serotonin - metabolism
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