Glycine crystallization in frozen and freeze-dried systems : Effect of pH and buffer concentration

(1) To determine the effect of solution pH before lyophilization, over the range of 1.5 to 10, on the salt and polymorphic forms of glycine crystallizing in frozen solutions and in lyophiles. (2) To quantify glycine crystallization during freezing and annealing as a function of solution pH before ly...

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Veröffentlicht in:Pharmaceutical research 2007-03, Vol.24 (3), p.593-604
Hauptverfasser: VARSHNEY, Dushyant B, KUMAR, Satyendra, SHALAEV, Evgenyi Y, SUNDARAMURTHI, Prakash, KANG, Shin-Woong, GATLIN, Larry A, SRYANARAYANAN, Raj
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