Elevated N-myristoyltransferase activity and expression in oral squamous cell carcinoma

N-myristoyltransferase (NMT) catalyzes the myristoylation of proteins involved in signal transduction, cellular transformation, differentiation, proliferation and oncogenesis. In this study, we report for the first time on the elevated NMT activity in oral squamous cell carcinoma (OSCC). Increased a...

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Veröffentlicht in:	Oncology reports 2007-07, Vol.18 (1), p.93-97
Hauptverfasser:	SHRIVASTAV, Anuraag, SHARMA, Anil R, BAJAJ, Gagan, CHARAVARYAMATH, Chandrashekhar, EZZAT, Wendelin, SPAFFORD, Peter, GORE-HICKMAN, Rick, SINGH, Baljit, COPETE, Maria A, SHARMA, Rajendra K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyltransferases - metabolism Biological and medical sciences Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - pathology Case-Control Studies Gene Expression Regulation, Neoplastic Humans Medical sciences Mouth Mucosa - enzymology Mouth Mucosa - pathology Mouth Neoplasms - enzymology Mouth Neoplasms - pathology Myristic Acid - metabolism Neoplasm Proteins - metabolism Otorhinolaryngology. Stomatology Protein Processing, Post-Translational Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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