Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device
Actinomycosis is an infectious disease that has been known since the late nineteenth century. In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii...
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Veröffentlicht in: | Laeknabladid 2007-06, Vol.93 (6), p.479-485 |
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description | Actinomycosis is an infectious disease that has been known since the late nineteenth century. In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii, is part of the commensal bacterial flora. It can infect any tissue, respects no tissue boundaries and can spread throughout the body. The clinical presentation of this illness can be similar to malignant disease and definite diagnosis is sometimes not apparent until after surgery and histologic examination. We report the case of a 71 year old woman who suffered from actinomycosis of the uterus and ovaries due to a forgotten intrauterine contraceptive device that had been in place for over four decades. The disease presentation was consistent with malignant disease and tumor markers, CA 125, CA 19-9 and CEA, measured in blood were elevated. She was treated successfully with total hysterectomy and bilateral salphingo-oophorectomy, as well as penicillin for six months. |
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In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii, is part of the commensal bacterial flora. It can infect any tissue, respects no tissue boundaries and can spread throughout the body. The clinical presentation of this illness can be similar to malignant disease and definite diagnosis is sometimes not apparent until after surgery and histologic examination. We report the case of a 71 year old woman who suffered from actinomycosis of the uterus and ovaries due to a forgotten intrauterine contraceptive device that had been in place for over four decades. The disease presentation was consistent with malignant disease and tumor markers, CA 125, CA 19-9 and CEA, measured in blood were elevated. She was treated successfully with total hysterectomy and bilateral salphingo-oophorectomy, as well as penicillin for six months.</description><identifier>ISSN: 0023-7213</identifier><identifier>PMID: 17541147</identifier><language>ice</language><publisher>Iceland</publisher><subject>Actinomycosis - diagnosis ; Actinomycosis - drug therapy ; Actinomycosis - etiology ; Actinomycosis - immunology ; Actinomycosis - surgery ; Aged ; Anti-Bacterial Agents - therapeutic use ; CA-125 Antigen - blood ; CA-19-9 Antigen - blood ; Carcinoembryonic Antigen - blood ; Diagnosis, Differential ; Female ; Humans ; Hysterectomy ; Intrauterine Devices - adverse effects ; Ovarian Diseases - diagnosis ; Ovarian Diseases - drug therapy ; Ovarian Diseases - etiology ; Ovarian Diseases - immunology ; Ovarian Diseases - surgery ; Ovariectomy ; Penicillins - therapeutic use ; Tomography, X-Ray Computed ; Treatment Outcome ; Uterine Diseases - diagnosis ; Uterine Diseases - drug therapy ; Uterine Diseases - etiology ; Uterine Diseases - immunology ; Uterine Diseases - surgery</subject><ispartof>Laeknabladid, 2007-06, Vol.93 (6), p.479-485</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17541147$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ingvarsson, Ragnar Freyr</creatorcontrib><creatorcontrib>Jónasson, Lárus</creatorcontrib><creatorcontrib>Saemundsson, Hafsteinn</creatorcontrib><creatorcontrib>Gottfredsson, Magnús</creatorcontrib><title>Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device</title><title>Laeknabladid</title><addtitle>Laeknabladid</addtitle><description>Actinomycosis is an infectious disease that has been known since the late nineteenth century. In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii, is part of the commensal bacterial flora. It can infect any tissue, respects no tissue boundaries and can spread throughout the body. The clinical presentation of this illness can be similar to malignant disease and definite diagnosis is sometimes not apparent until after surgery and histologic examination. We report the case of a 71 year old woman who suffered from actinomycosis of the uterus and ovaries due to a forgotten intrauterine contraceptive device that had been in place for over four decades. The disease presentation was consistent with malignant disease and tumor markers, CA 125, CA 19-9 and CEA, measured in blood were elevated. She was treated successfully with total hysterectomy and bilateral salphingo-oophorectomy, as well as penicillin for six months.</description><subject>Actinomycosis - diagnosis</subject><subject>Actinomycosis - drug therapy</subject><subject>Actinomycosis - etiology</subject><subject>Actinomycosis - immunology</subject><subject>Actinomycosis - surgery</subject><subject>Aged</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>CA-125 Antigen - blood</subject><subject>CA-19-9 Antigen - blood</subject><subject>Carcinoembryonic Antigen - blood</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Intrauterine Devices - adverse effects</subject><subject>Ovarian Diseases - diagnosis</subject><subject>Ovarian Diseases - drug therapy</subject><subject>Ovarian Diseases - etiology</subject><subject>Ovarian Diseases - immunology</subject><subject>Ovarian Diseases - surgery</subject><subject>Ovariectomy</subject><subject>Penicillins - therapeutic use</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><subject>Uterine Diseases - diagnosis</subject><subject>Uterine Diseases - drug therapy</subject><subject>Uterine Diseases - etiology</subject><subject>Uterine Diseases - immunology</subject><subject>Uterine Diseases - surgery</subject><issn>0023-7213</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1rwzAYhDW0NCHNXyiauhkkS5biMYR-QaBLoKN5Lb1qVWzLleSE_Pu6NLnlOO7hhrshS8ZKUeiSiwVZp_TNZinG61rfkQXXleRc6iX52Jrsh9CfTUg-UT9QoJrRM0KkobP0FHoY6Mnnr7lwIX6GnHGYuRxhyhj9gNSEv2RwzP6I1OLRG7wntw66hOuLr8jh-emwey327y9vu-2-GCupC6m0FYDYascZd3xT1i1s0NaAzkmmSitbDoppYNKBq0BskHPDrFZWl1UrVuTxf3aM4WfClJveJ4NdBwOGKTWaVYoLrWbw4QJObY-2GaPvIZ6b6xPiFyCTWuk</recordid><startdate>200706</startdate><enddate>200706</enddate><creator>Ingvarsson, Ragnar Freyr</creator><creator>Jónasson, Lárus</creator><creator>Saemundsson, Hafsteinn</creator><creator>Gottfredsson, Magnús</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200706</creationdate><title>Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device</title><author>Ingvarsson, Ragnar Freyr ; 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In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii, is part of the commensal bacterial flora. It can infect any tissue, respects no tissue boundaries and can spread throughout the body. The clinical presentation of this illness can be similar to malignant disease and definite diagnosis is sometimes not apparent until after surgery and histologic examination. We report the case of a 71 year old woman who suffered from actinomycosis of the uterus and ovaries due to a forgotten intrauterine contraceptive device that had been in place for over four decades. The disease presentation was consistent with malignant disease and tumor markers, CA 125, CA 19-9 and CEA, measured in blood were elevated. She was treated successfully with total hysterectomy and bilateral salphingo-oophorectomy, as well as penicillin for six months.</abstract><cop>Iceland</cop><pmid>17541147</pmid><tpages>7</tpages></addata></record> |
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subjects | Actinomycosis - diagnosis Actinomycosis - drug therapy Actinomycosis - etiology Actinomycosis - immunology Actinomycosis - surgery Aged Anti-Bacterial Agents - therapeutic use CA-125 Antigen - blood CA-19-9 Antigen - blood Carcinoembryonic Antigen - blood Diagnosis, Differential Female Humans Hysterectomy Intrauterine Devices - adverse effects Ovarian Diseases - diagnosis Ovarian Diseases - drug therapy Ovarian Diseases - etiology Ovarian Diseases - immunology Ovarian Diseases - surgery Ovariectomy Penicillins - therapeutic use Tomography, X-Ray Computed Treatment Outcome Uterine Diseases - diagnosis Uterine Diseases - drug therapy Uterine Diseases - etiology Uterine Diseases - immunology Uterine Diseases - surgery |
title | Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device |
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