Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device

Actinomycosis is an infectious disease that has been known since the late nineteenth century. In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii...

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Veröffentlicht in:Laeknabladid 2007-06, Vol.93 (6), p.479-485
Hauptverfasser: Ingvarsson, Ragnar Freyr, Jónasson, Lárus, Saemundsson, Hafsteinn, Gottfredsson, Magnús
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container_start_page 479
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creator Ingvarsson, Ragnar Freyr
Jónasson, Lárus
Saemundsson, Hafsteinn
Gottfredsson, Magnús
description Actinomycosis is an infectious disease that has been known since the late nineteenth century. In the pre-antibiotic era it was thought to be rather common but with increased use of antimicrobial agents its incidence has decreased significantly. The causative agent, most commonly Actinomyces israelii, is part of the commensal bacterial flora. It can infect any tissue, respects no tissue boundaries and can spread throughout the body. The clinical presentation of this illness can be similar to malignant disease and definite diagnosis is sometimes not apparent until after surgery and histologic examination. We report the case of a 71 year old woman who suffered from actinomycosis of the uterus and ovaries due to a forgotten intrauterine contraceptive device that had been in place for over four decades. The disease presentation was consistent with malignant disease and tumor markers, CA 125, CA 19-9 and CEA, measured in blood were elevated. She was treated successfully with total hysterectomy and bilateral salphingo-oophorectomy, as well as penicillin for six months.
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subjects Actinomycosis - diagnosis
Actinomycosis - drug therapy
Actinomycosis - etiology
Actinomycosis - immunology
Actinomycosis - surgery
Aged
Anti-Bacterial Agents - therapeutic use
CA-125 Antigen - blood
CA-19-9 Antigen - blood
Carcinoembryonic Antigen - blood
Diagnosis, Differential
Female
Humans
Hysterectomy
Intrauterine Devices - adverse effects
Ovarian Diseases - diagnosis
Ovarian Diseases - drug therapy
Ovarian Diseases - etiology
Ovarian Diseases - immunology
Ovarian Diseases - surgery
Ovariectomy
Penicillins - therapeutic use
Tomography, X-Ray Computed
Treatment Outcome
Uterine Diseases - diagnosis
Uterine Diseases - drug therapy
Uterine Diseases - etiology
Uterine Diseases - immunology
Uterine Diseases - surgery
title Actinomycosis in a 70 year old woman with a forgotten intrauterine contraceptive device
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