VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly

1 Department of Pharmaceutical Chemistry, University of Kansas, Lawrence 66047; and 2 Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045 Tight junctions between brain microvessel endothelial cells (BMECs) maintain the blood-brain barrier. Barrier breakdown is associa...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2001-01, Vol.280 (1), p.H434-H440
Hauptverfasser:	Wang, Wen, Dentler, William L, Borchardt, Ronald T
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Blotting, Western Brain - blood supply Cattle Cell Membrane Permeability Cells, Cultured Electric Impedance Endothelial Growth Factors - pharmacology Endothelial Growth Factors - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Immunohistochemistry Lymphokines - pharmacology Lymphokines - physiology Membrane Proteins - biosynthesis Membrane Proteins - genetics Microcirculation Occludin Sucrose - metabolism Tight Junctions - drug effects Tight Junctions - physiology Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors
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