A Novel Atopic Dermatitis Model Induced by Topical Application with Dermatophagoides Farinae Extract in NC/Nga Mice

Atopic dermatitis is a chronically relapsing inflammatory skin disease. Animal models induced by relevant allergens play a very important role in the elucidation of the disease. The patients with atopic dermatitis are highly sensitized with mite allergens such as Dermatophagoides farinae (Df). There...

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Veröffentlicht in:	Allergology international 2007, Vol.56 (2), p.139-148
Hauptverfasser:	Yamamoto, Mina, Haruna, Takayo, Yasui, Kiyoshi, Takahashi, Hisashi, Iduhara, Miho, Takaki, Shigeki, Deguchi, Masashi, Arimura, Akinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - pharmacology Adrenal Cortex Hormones - therapeutic use Allergens - immunology animal model Animals atopic dermatitis Betamethasone - analogs & derivatives Betamethasone - pharmacology Betamethasone - therapeutic use Dermatitis, Atopic - drug therapy Dermatitis, Atopic - immunology Dermatitis, Atopic - metabolism Dermatitis, Atopic - pathology Dermatophagoides farinae Dermatophagoides farinae - immunology Disease Models, Animal Drug Evaluation, Preclinical - methods Female house dust mite Immunoglobulin E - blood Immunosuppressive Agents - pharmacology Immunosuppressive Agents - therapeutic use Interferon-gamma - metabolism Interleukin-13 - metabolism Interleukin-5 - metabolism Lymph Nodes - immunology Lymph Nodes - metabolism Mice NC/Nga mice Reproducibility of Results Skin - drug effects Skin - immunology Skin - pathology Tacrolimus - pharmacology Tacrolimus - therapeutic use
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