Utilizing the Peptidyl-Prolyl Cis-Trans Isomerase Pin1 as a Probe of Its Phosphorylated Target Proteins: Examples of Binding to Nuclear Proteins in a Human Kidney Cell Line and to Tau in Alzheimer's Diseased Brain

The human parvulin Pin1 is a member of the peptidyl–prolyl cis–trans isomerase group of proteins, which modulate the assembly, folding, activity, and transport of essential cellular proteins. Pin1 is a mitotic regulator interacting with a range of proteins that are phosphorylated before cell divisio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of histochemistry and cytochemistry 2001-01, Vol.49 (1), p.97-107
Hauptverfasser:	Thorpe, Julian R., Morley, Simon J., Rulten, Stuart L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Brain - metabolism Cell Line Cell Nucleus - metabolism Humans Hydrogen-Ion Concentration Immunohistochemistry - methods Kidney - cytology Male Middle Aged Mitosis Molecular Probes NIMA-Interacting Peptidylprolyl Isomerase Nocodazole - pharmacology Nuclear Proteins - metabolism Peptidylprolyl Isomerase - chemistry Peptidylprolyl Isomerase - metabolism Phosphorylation Protein Binding Serine - metabolism tau Proteins - metabolism Threonine - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!