Bi-Directional Activation Between Human Airway Smooth Muscle Cells and T Lymphocytes: Role in Induction of Altered Airway Responsiveness

Because both T lymphocyte and airway smooth muscle (ASM) cell activation are events fundamentally implicated in the pathobiology of asthma, this study tested the hypothesis that cooperative intercellular signaling between activated T cells and ASM cells mediates proasthmatic changes in ASM responsiv...

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Veröffentlicht in:	The Journal of immunology (1950) 2001-01, Vol.166 (1), p.293-303
Hauptverfasser:	Hakonarson, Hakon, Kim, Cecilia, Whelan, Russel, Campbell, Donald, Grunstein, Michael M
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion molecules Adolescent Adult Animals Cell Adhesion Molecules - biosynthesis Cell Adhesion Molecules - metabolism Cell Communication - immunology Humans In Vitro Techniques Lymphocyte Activation Male Muscle Contraction - immunology Muscle Relaxation - immunology Muscle, Smooth - cytology Muscle, Smooth - immunology Muscle, Smooth - metabolism Muscle, Smooth - physiopathology Rabbits T-Lymphocytes - immunology T-Lymphocytes - metabolism Trachea - cytology Trachea - immunology Trachea - metabolism Trachea - physiopathology
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