iPTREE-STAB: interpretable decision tree based method for predicting protein stability changes upon mutations

We have developed a web server, iPTREE-STAB for discriminating the stability of proteins (stabilizing or destabilizing) and predicting their stability changes (ΔΔG) upon single amino acid substitutions from amino acid sequence. The discrimination and prediction are mainly based on decision tree coup...

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Veröffentlicht in:	Bioinformatics 2007-05, Vol.23 (10), p.1292-1293
Hauptverfasser:	Huang, Liang-Tsung, Gromiha, M. Michael, Ho, Shinn-Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Amino Acid Substitution Biological and medical sciences Fundamental and applied biological sciences. Psychology General aspects Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Mutation Protein Conformation Proteins - chemistry Proteins - genetics Thermodynamics
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