Extremely Thermophilic Translation System in the Common Ancestor Commonote: Ancestral Mutants of Glycyl-tRNA Synthetase from the Extreme Thermophile Thermus thermophilus

Based on phylogenetic analysis of 16 S and 18 S rRNAs, the common ancestor of all organisms (Commonote) was proposed to be hyperthermophilic. We have previously tested this hypothesis using enzymes with ancestral residues that are inferred by molecular phylogenetic analysis. The ancestral mutant enz...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular biology 2007-06, Vol.369 (4), p.1060-1069
Hauptverfasser:	Shimizu, Hideaki, Yokobori, Shin-ichi, Ohkuri, Takatoshi, Yokogawa, Takashi, Nishikawa, Kazuya, Yamagishi, Akihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence ancestral residue Archaeal Proteins - genetics Archaeal Proteins - metabolism Bacterial Proteins - chemistry Bacterial Proteins - classification Bacterial Proteins - genetics Bacterial Proteins - metabolism Commonote, universal common ancestor Enzyme Stability Escherichia coli Evolution, Molecular Glycine-tRNA Ligase - chemistry Glycine-tRNA Ligase - classification Glycine-tRNA Ligase - genetics Glycine-tRNA Ligase - metabolism glycyl-tRNA synthetase Models, Molecular Molecular Sequence Data Phylogeny Protein Biosynthesis protein stability Protein Structure, Quaternary Sequence Alignment Thermus thermophilus Thermus thermophilus - enzymology Thermus thermophilus - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!