A green tea extract lowers plasma cholesterol by inhibiting cholesterol synthesis and upregulating the LDL receptor in the cholesterol-fed rabbit

Abstract Green tea extracts enriched in catechins decrease plasma cholesterol in hamsters, mice and rats. The aims of this study were to determine whether a catechin-enriched extract of green tea could lower plasma cholesterol in the cholesterol-fed rabbit and to determine the mechanism of action. F...

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Veröffentlicht in:	Atherosclerosis 2007-07, Vol.193 (1), p.86-93
Hauptverfasser:	Bursill, Christina A, Abbey, Mavis, Roach, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - isolation & purification Anticholesteremic Agents - pharmacology Aorta Aorta, Thoracic - drug effects Aorta, Thoracic - metabolism Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Camellia sinensis - chemistry Cardiology. Vascular system Cardiovascular Catechin - isolation & purification Catechin - pharmacology Cholesterol - biosynthesis Cholesterol - blood Cholesterol absorption Cholesterol synthesis Cholesterol, Dietary - administration & dosage Coronary heart disease Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Green tea Heart Lathosterol LDL receptor Liver - drug effects Liver - metabolism Male Medical sciences Phytosterols Plant Extracts - isolation & purification Plant Extracts - pharmacology Rabbits Receptors, LDL - metabolism Tea - chemistry Up-Regulation - drug effects
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