Intervertebral Disc Regeneration Using Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel Microspheres

This study evaluated the regenerative effects of platelet-rich plasma (PRP) for the degenerated intervertebral disc (IVD) in vivo . After induction of IVD degeneration in rabbits, we prepared PRP by centrifuging blood obtained from these rabbits. These PRP were injected into the nucleus pulposus (NP...

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Veröffentlicht in:	Tissue engineering 2007-01, Vol.13 (1), p.147-158
Hauptverfasser:	Nagae, Masateru, Ikeda, Takumi, Mikami, Yasuo, Hase, Hitoshi, Ozawa, Hitoshi, Matsuda, Ken-Ichi, Sakamoto, Hirotaka, Tabata, Yasuhiko, Kawata, Mitsuhiro, Kubo, Toshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Animals Bone Regeneration - physiology Drug Delivery Systems Gelatin - chemical synthesis Hydrogels - chemical synthesis Intercellular Signaling Peptides and Proteins - blood Intervertebral Disc - pathology Intervertebral Disc - physiopathology Intervertebral Disc - ultrastructure Intervertebral Disc Displacement - blood Intervertebral Disc Displacement - physiopathology Intervertebral Disc Displacement - therapy Male Microspheres Platelet Count Platelet-Rich Plasma - physiology Rabbits
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