Pharmacokinetics and metabolism of sirolimus

Sirolimus (rapamycin, Rapamune) is a potent immunosuppressive drug that received marketing approval from the US Food and Drug Administration on September 15, 1999. Research into defining its pharmacokinetic (PK) behavior, interaction with other agents, and metabolism is ongoing. It has been establis...

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Veröffentlicht in:	Therapeutic drug monitoring 2000-02, Vol.22 (1), p.31-35
Hauptverfasser:	GALLANT-HAIDNER, H. L, TREPANIER, D. J, FREITAG, D. G, YATSCOFF, R. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biotransformation Clinical Trials as Topic Humans Immunomodulators Immunosuppressive Agents - metabolism Immunosuppressive Agents - pharmacokinetics Medical sciences Pharmacology. Drug treatments Sirolimus - metabolism Sirolimus - pharmacokinetics
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