Immunohistochemical expression of β-catenin, E-cadherin, cyclin D1 and c-myc in benign trichogenic tumors

Background:  β‐catenin gene mutations have been reported in vast majority of pilomatrixomas (PMXs). β‐catenin, a component of the adhesion molecules of the cytoskeleton, is degraded at the cytoplasm. Excess cytoplasmic β‐catenin enters into the nucleus and activates the transcription of several gene...

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