Calcium and neurodegeneration

Summary When properly controlled, Ca2+ fluxes across the plasma membrane and between intracellular compartments play critical roles in fundamental functions of neurons, including the regulation of neurite outgrowth and synaptogenesis, synaptic transmission and plasticity, and cell survival. During a...

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Veröffentlicht in:	Aging cell 2007-06, Vol.6 (3), p.337-350
1. Verfasser:	Mattson, Mark P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease amyloid Amyloid - chemistry Animals Apoptosis Calcium - metabolism Calcium Signaling endoplasmic reticulum Endoplasmic Reticulum - metabolism Humans Microscopy, Fluorescence Models, Biological Nerve Degeneration Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology N‐methyl‐d‐aspartate Oxidative Stress Parkinson Disease - genetics Parkinson Disease - metabolism Parkinson's disease presenilin Presenilins - metabolism
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