Dopamine Transporter 3′-UTR VNTR Genotype and ADHD: a Pharmaco-Behavioural Genetic Study with Methylphenidate

We sought to test the hypothesis that the variable number of tandem repeat (VNTR) polymorphism in the 3′-untranslated region (3′-UTR) of the SLC6A3 gene modulates behavior in children with ADHD and/or behavioral response to methylphenidate (MPH). One hundred and fifty-nine children with AHDH (6–12 y...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2007-06, Vol.32 (6), p.1370-1376
Hauptverfasser:	Joober, Ridha, Grizenko, Natalie, Sengupta, Sarojini, Amor, Leila Ben, Schmitz, Norbert, Schwartz, George, Karama, Sherif, Lageix, Philippe, Fathalli, Ferid, Torkaman-Zehi, Adam, Stepanian, Marina Ter
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - genetics Attention Deficit Disorder with Hyperactivity - psychology Attention deficit hyperactivity disorder Behavior Behavioral Sciences Biological and medical sciences Biological Psychology Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - therapeutic use Child Child & adolescent psychiatry Cross-Over Studies Dopamine Dopamine Plasma Membrane Transport Proteins - genetics Female Genotype Genotype & phenotype Humans Hypotheses Male Medical sciences Medicine Medicine & Public Health Methylphenidate - administration & dosage Methylphenidate - therapeutic use Minisatellite Repeats - genetics Neuropharmacology Neurosciences original-article Pharmacology. Drug treatments Pharmacotherapy Polymorphism Polymorphism, Genetic - genetics Prospective Studies Psychiatric Status Rating Scales Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Research centers Schools
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