Cooperative mechanisms of mitotic spindle formation

Cooperativity is well known to promote the speed of some biochemical reactions by accelerating the activity of enzymes. Recent studies have shown that cooperative interactions also function during the formation of a complex cellular structure, the mitotic spindle. Capture of kinetochores by dynamic...

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Veröffentlicht in:	Journal of cell science 2007-05, Vol.120 (10), p.1717-1722
Hauptverfasser:	O'Connell, Christopher B, Khodjakov, Alexey L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Centrosome - metabolism Centrosome - ultrastructure Chromosome Segregation - genetics Humans Kinetochores - metabolism Kinetochores - ultrastructure Microtubules - metabolism Microtubules - ultrastructure Mitosis - physiology ran GTP-Binding Protein - metabolism Signal Transduction - physiology Spindle Apparatus - metabolism Spindle Apparatus - ultrastructure
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