A microsurgical approach to hepatic and extrahepatic antigen presentation and its effects on the migration pattern of activated CD8+ T cells

CD8+T lymphocytes activated in peripheral lymphoid organs are believed to preferentially localize to the hepatic sinusoids, but the role of antigen in the process has been difficult to define. To create experimental mice in which the liver was unique in lacking the ability to present antigen, we ado...

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