G Protein regulation of MAPK networks

G proteins provide signal-coupling mechanisms to heptahelical cell surface receptors and are critically involved in the regulation of different mitogen-activated protein kinase (MAPK) networks. The four classes of G proteins, defined by the G s , G i , G q and G 12 families, regulate ERK1/2, JNK, p3...

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Veröffentlicht in:	Oncogene 2007-05, Vol.26 (22), p.3122-3142
Hauptverfasser:	Goldsmith, Z G, Dhanasekaran, D N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cancer Cancer cells Cell Biology Cell surface Extracellular signal-regulated kinase G protein-coupled receptors G proteins Genetic aspects Genetics GTP-Binding Proteins - physiology Health aspects Human Genetics Humans Intermediates Internal Medicine Kinases MAP kinase MAP Kinase Signaling System - physiology Medicine Medicine & Public Health Mitogen-Activated Protein Kinases - metabolism Mitogen-Activated Protein Kinases - physiology Oncology Physiological aspects Protein kinase Protein kinases Proteins review Signal transduction Tyrosine
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