Microalgae as cell factories producing recombinant commercial proteins

Extraction of natural substances and chemical synthesis are the main sources of pharmaceutical molecules. When possible, one may transfer the gene of the molecule in living cells creating individual factories producing on demand and in a safe way the requested molecule. Today, bacteria, yeast, mamma...

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Veröffentlicht in:	M.S. Médecine sciences 2008-04, Vol.24 (4), p.375-382
Hauptverfasser:	Cadoret, Jean-Paul, Bardor, Muriel, Lerouge, Patrice, Cabigliera, Morgan, Henriquez, Vitalia, Carlier, Aude
Format:	Artikel
Sprache:	fre
Schlagworte:	Animals Chloroplasts - physiology Commerce Eukaryota - genetics Eukaryota - physiology Gene Silencing Mice Mice, Transgenic Models, Biological Proteins - genetics Recombinant Proteins - biosynthesis
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Beschreibung
Zusammenfassung:	Extraction of natural substances and chemical synthesis are the main sources of pharmaceutical molecules. When possible, one may transfer the gene of the molecule in living cells creating individual factories producing on demand and in a safe way the requested molecule. Today, bacteria, yeast, mammalian cells and plants constitute the main plate-forms for various commercial products. Microalgae present numerous advantages and could offer a powerful tool for the production of commercial molecules in a near future.
ISSN:	0767-0974
DOI:	10.1051/medsci/2008244375