FDG–PET Imaging in the Investigation of Homonymous Hemianopia in a Patient With MELAS Syndrome
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare congenital disorder of mitochondrial DNA. Patients with MELAS syndrome present with a range of clinical symptoms including headaches, hearing loss, visual defects, and hemiparesis. We report...
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| Veröffentlicht in: | Clinical nuclear medicine 2007-06, Vol.32 (6), p.479-480 |
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| creator | Shelly, Martin J Kelly, Peter O’Connell, Martin J |
| description | Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare congenital disorder of mitochondrial DNA. Patients with MELAS syndrome present with a range of clinical symptoms including headaches, hearing loss, visual defects, and hemiparesis. We report a case of a previously asymptomatic 21-year-old male who presented with recurrent headache, seizures, and right homonymous hemianopia. Investigations included brain MRI, which indicated bilateral occipital white matter and cortical signal abnormality and fluorodeoxyglucose (FDG)–PET brain imaging which demonstrated markedly reduced metabolism in the occipital lobes. The patient was treated with corticosteroids and coenzyme Q and his clinical symptoms have improved. |
| doi_str_mv | 10.1097/RLU.0b013e3180537852 |
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| language | eng |
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| subjects | Adult Diagnosis, Differential Fluorodeoxyglucose F18 Hemianopsia - diagnostic imaging Humans Imaging, Three-Dimensional Magnetic Resonance Imaging Male MELAS Syndrome - diagnostic imaging Radiopharmaceuticals Tomography, Emission-Computed |
| title | FDG–PET Imaging in the Investigation of Homonymous Hemianopia in a Patient With MELAS Syndrome |
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