Pro-inflammatory cytokine inhibition in the primate using microencapsulated antisense oligomers to NF-kappaB

Antisense oligomers to NF-kappaB (ASO) were incorporated into albumin microspheres to determine if microcapsules containing ASO inhibit pro-inflammatory cytokines to a greater extent than comparable doses of ASO in solution. Phagocytosis of microcapsules and intracellular release of ASO in macrophag...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of microencapsulation 2007-06, Vol.24 (4), p.337-348
Hauptverfasser:	Oettinger, Carl W, D'souza, Martin J, Akhavein, Nima, Peer, Glenn T, Taylor, Fletcher B, Kinasewitz, Gary T
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Capsules Cytokines - antagonists & inhibitors Emulsions Inflammation - physiopathology Macrophages - drug effects Macrophages - physiology Mice Microspheres NF-kappa B - genetics Oligonucleotides, Antisense - pharmacology Papio Serum Albumin, Bovine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!