Melatonin inhibitory effect on cAMP accumulation in the chick retina development

During vertebrate neurodevelopment, neuritogenesis and synaptogenesis are modulated by intracellular cAMP rises. Melatonin, which is implicated in neuronal differentiation, mainly inhibits this pathway. Here, an investigation about the profile of this effect during the vertebrate neurodevelopment is...

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Veröffentlicht in:	International journal of developmental neuroscience 2008-05, Vol.26 (3-4), p.277-282
1. Verfasser:	Sampaio, Lucia de Fatima Sobral
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive - drug effects Binding, Competitive - physiology cAMP Cell Differentiation - drug effects Cell Differentiation - physiology Chick Embryo Colforsin - pharmacology Cyclic AMP - antagonists & inhibitors Cyclic AMP - metabolism Dose-Response Relationship, Drug Melatonin Melatonin - pharmacology Melatonin - physiology Neurodevelopment Neurons - drug effects Neurons - metabolism Phosphodiesterase Inhibitors - pharmacology Receptor, Melatonin, MT2 - agonists Receptor, Melatonin, MT2 - antagonists & inhibitors Receptor, Melatonin, MT2 - metabolism Retina Retina - drug effects Retina - embryology Retina - metabolism Tetrahydronaphthalenes - pharmacology Tryptamines - pharmacology
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