Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa

The automated docking program DOCK 5.3.0 was applied to screening for quorum sensing inhibitors (QSIs) of Peudomonus aeruginosa from a database containing 51 active components of Traditional Chinese Medicines with antibacterial activity. Five potential QSIs were revealed by the computer-based virtua...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied microbiology and biotechnology 2008-05, Vol.79 (1), p.119-126
Hauptverfasser:	Zeng, Zhirui, Qian, Li, Cao, Lixiang, Tan, Hongming, Huang, Yali, Xue, Xiaoli, Shen, Yong, Zhou, Shining
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Anti-Bacterial Agents - pharmacology Antibiotics Applied Microbial and Cell Physiology Bacteria Bacterial Proteins - antagonists & inhibitors Baicalein biofilm Biofilms Biofilms - drug effects Biological and medical sciences Biotechnology Chinese medicine Cloning Computer-Aided Design Crystal structure Databases, Factual Drug Design Drug Evaluation, Preclinical Drugs E coli Escherichia coli Escherichia coli - drug effects Escherichia coli - metabolism Flavanones - pharmacology Fundamental and applied biological sciences. Psychology Genes Gram-negative bacteria Herbal medicine Life Sciences Ligands Medicine, Chinese Traditional Microbial Genetics and Genomics Microbiology Models, Molecular Peudomonus aeruginosa Plasmids Proteins Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Quorum Sensing - drug effects Quorum sensing inhibitor Software Spheres Studies Traditional Chinese Medicine Virtual screening
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!