Plasma Glutamate and Glycine Levels in Patients with Amyotrophic Lateral Sclerosis

Defective glutamate (Glu) metabolism and glutamate excitotoxicity have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Glycine (Gly), the main inhibitory neurotransmitter, has been shown to potentiate excitatory transmission. In the present study, the levels of Glu and Gl...

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Veröffentlicht in:	In vivo (Athens) 2008-01, Vol.22 (1), p.137-141
Hauptverfasser:	Andreadou, Elisabeth, Kapaki, Elisabeth, Kokotis, Panagiotis, Paraskevas, George P, Katsaros, Nikolaos, Libitaki, Georgia, Petropoulou, Olga, Zis, Vassilios, Sfagos, Constantinos, Vassilopoulos, Demetrios
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic Lateral Sclerosis - blood Amyotrophic Lateral Sclerosis - diagnosis Amyotrophic Lateral Sclerosis - physiopathology Chromatography, High Pressure Liquid Female Food Deprivation Glutamic Acid - blood Glycine - blood Humans Male Middle Aged Severity of Illness Index
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