Smt3 is required for Drosophila melanogaster metamorphosis

Sumoylation, the covalent attachment of the small ubiquitin-related modifier SUMO to target proteins, regulates different cellular processes, although its role in the control of development remains unclear. We studied the role of sumoylation during Drosophila development by using RNAi to reduce smt3...

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Veröffentlicht in:	Development (Cambridge) 2008-05, Vol.135 (9), p.1659-1668
Hauptverfasser:	Talamillo, Ana, Sánchez, Jonatan, Cantera, Rafael, Pérez, Coralia, Martín, David, Caminero, Eva, Barrio, Rosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - metabolism Cholesterol - biosynthesis Cytoplasm - metabolism Drosophila melanogaster - growth & development Drosophila melanogaster - metabolism Drosophila melanogaster - physiology Drosophila Proteins - genetics Drosophila Proteins - physiology Ecdysteroids - biosynthesis Ecdysterone - pharmacology Larva - growth & development Larva - physiology Lipids - biosynthesis Metamorphosis, Biological - physiology Pupa - growth & development Pupa - physiology Repressor Proteins - genetics Repressor Proteins - physiology
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