Environment-Sensitive Two-Photon Probe for Intracellular Free Magnesium Ions in Live Tissue

“Green” emission: A novel two‐photon fluorescent probe that can detect intracellular free Mg2+ ions at a depth of a few hundred micrometers in live tissue was developed. The emission from the Mg2+–probe complex (green) shows little interference from association of the probe with other intracellular...

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Veröffentlicht in:	Angewandte Chemie International Edition 2007-01, Vol.46 (19), p.3460-3463
Hauptverfasser:	Kim, Hwan Myung, Jung, Cheol, Kim, Bo Ra, Jung, Soon-Young, Hong, Jin Hee, Ko, Young-Gyu, Lee, Kyoung J., Cho, Bong Rae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cations, Divalent Fluorescent Dyes - chemistry fluorescent probes Hippocampus - cytology Hippocampus - pathology Humans imaging agents Intracellular Space - metabolism Liver - cytology Liver - pathology magnesium Magnesium - analysis Magnesium - metabolism Mice Photons Spectrometry, Fluorescence two‒photon processes
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Beschreibung
Zusammenfassung:	“Green” emission: A novel two‐photon fluorescent probe that can detect intracellular free Mg2+ ions at a depth of a few hundred micrometers in live tissue was developed. The emission from the Mg2+–probe complex (green) shows little interference from association of the probe with other intracellular metal ions or with the cell membrane (blue).
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200700169