Exercise promotes angiogenesis and improves β-adrenergic receptor signalling in the post-ischaemic failing rat heart

Aims We investigated whether exercise training could promote angiogenesis and improve blood perfusion and left ventricular (LV) remodelling of the post-myocardial infarction (MI) failing heart. We also explored the contribution of ameliorated β-adrenergic receptor signalling and function on the over...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular research 2008-05, Vol.78 (2), p.385-394
Hauptverfasser:	Leosco, Dario, Rengo, Giuseppe, Iaccarino, Guido, Golino, Luca, Marchese, Massimo, Fortunato, Francesca, Zincarelli, Carmela, Sanzari, Emma, Ciccarelli, Michele, Galasso, Gennaro, Altobelli, Giovanna Giuseppina, Conti, Valeria, Matrone, Gianfranco, Cimini, Vincenzo, Ferrara, Nicola, Filippelli, Amelia, Koch, Walter J., Rengo, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - pharmacology Angiogenesis Animals Coronary Circulation Coronary Vessels - drug effects Coronary Vessels - metabolism Coronary Vessels - physiopathology Disease Models, Animal Dose-Response Relationship, Drug Exercise training Heart failure Heart Failure - diagnostic imaging Heart Failure - etiology Heart Failure - metabolism Heart Failure - physiopathology Isoproterenol - pharmacology Male Myocardial Contraction Myocardial Infarction - complications Myocardial Infarction - diagnostic imaging Myocardial Infarction - metabolism Myocardial Infarction - physiopathology Myocardium - enzymology Myocardium - metabolism Myocardium - pathology Neovascularization, Physiologic - drug effects Nitric Oxide Synthase Type II - metabolism Nitric Oxide Synthase Type III Physical Exertion Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Wistar Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - metabolism Signal Transduction - drug effects Time Factors Ultrasonography Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Ventricular Function, Left Ventricular Remodeling β-adrenergic receptor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!