A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner

To effectively treat serious bone defects using bone regenerative medicine, there is a need for the development of a small chemical compound that potently induces bone formation. We now report a novel osteogenic helioxanthin-derivative, TH. TH induced osteogenic differentiation in MC3T3-E1 cells, mo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2007-06, Vol.357 (4), p.854-860
Hauptverfasser:	Ohba, Shinsuke, Nakajima, Keiji, Komiyama, Yusuke, Kugimiya, Fumitaka, Igawa, Kazuyo, Itaka, Keiji, Moro, Toru, Nakamura, Kozo, Kawaguchi, Hiroshi, Takato, Tsuyoshi, Chung, Ung-il
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals BMP Bone Morphogenetic Protein 2 Bone Morphogenetic Proteins - administration & dosage Bone regeneration Cell Differentiation - drug effects Dose-Response Relationship, Drug Drug Combinations ES cell Fibroblast Lignans Mice Osteoblast Osteoblasts - cytology Osteoblasts - drug effects Osteogenesis - drug effects Osteogenesis - physiology Osteogenic differentiation Small compound Transforming Growth Factor beta - administration & dosage Xanthines - administration & dosage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!