Inhibition of Ulmus davidiana Planch (Ulmaceae) on bone resorption mediated by processing of Cathepsin K in cultured mouse osteoclasts

Ulmus davidiana Planch (Ulmaceae) (UD) has long been known to be antiinflammatory in traditional Korean medicine. This experiment investigated the effects of UD on bone resorption using bone cell culture. Different concentrations of crude extract of UD were added to mouse bone cell culture. The mito...

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Veröffentlicht in:	Phytotherapy research 2008-04, Vol.22 (4), p.511-517
Hauptverfasser:	Kim, Kyung-Woon, Park, Jun-Sung, Kim, Kap-Sung, Jin, Un-Ho, Kim, June-Ki, Suh, Seok-Jong, Kim, Cheorl-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences biosynthesis bone resorption Bone Resorption - enzymology Bone Resorption - prevention & control cathepsin Cathepsin K Cathepsins - metabolism Dose-Response Relationship, Drug General pharmacology Immunoblotting Immunoprecipitation Korean herbal medicine Medical sciences Mice osteoclast Osteoclasts - cytology Osteoclasts - drug effects Osteoclasts - enzymology osteoporosis Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology processing protease inhibitor Ulmus - chemistry Ulmus davidiana Planch (Ulmaceae) Ulmus davidiana Planch (Ulmaceae) Korean herbal medicine
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