In vivo temporal property of GABAergic neural transmission in collateral feed-forward inhibition system of hippocampal–prefrontal pathway

Abstract Anatomical evidence suggests that rat CA1 hippocampal afferents collaterally innervate excitatory projecting pyramidal neurons and inhibitory interneurons, creating a disynaptic, feed-forward inhibition microcircuit in the medial prefrontal cortex (mPFC). We investigated the temporal relati...

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Veröffentlicht in:	Brain research 2007-05, Vol.1150, p.69-73
Hauptverfasser:	Takita, Masatoshi, Kuramochi, Masahito, Izaki, Yoshinori, Ohtomi, Michiko
Format:	Artikel
Sprache:	eng
Schlagworte:	( R)-baclofen ( RS)-saclofen (−)-Bicuculline Afferent Pathways Analysis of Variance Animals Biological and medical sciences Central nervous system CGP46381 ((3-aminopropyl)(cyclohexylmethyl)-phosphinic acid) Dose-Response Relationship, Drug Electric Stimulation - methods Electrophysiology Evoked Potentials - drug effects Evoked Potentials - physiology Evoked Potentials - radiation effects Fundamental and applied biological sciences. Psychology GABA Agents - pharmacology gamma-Aminobutyric Acid - metabolism gamma-Aminobutyric Acid - pharmacology Hippocampus - cytology Male Microdialysis Muscimol Neural Inhibition - drug effects Neural Inhibition - physiology Neural Inhibition - radiation effects Neurology Neurons - classification Neurons - physiology Neurons - radiation effects Paired-pulse facilitation Prefrontal cortex Prefrontal Cortex - physiology Rats Rats, Sprague-Dawley Synaptic Transmission - drug effects Synaptic Transmission - physiology Synaptic Transmission - radiation effects Time Factors Vertebrates: nervous system and sense organs
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