New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma

The concept of mesenchymal fibroblasts has evolved over the past two decades from a relatively inert structural cell type to a dynamic, pluripotent cell lineage controlling normal connective tissue formation, homeostasis, and repair and as principle players in pathogenic scarring and fibrosis. In wo...

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Veröffentlicht in:	Current rheumatology reports 2007-05, Vol.9 (2), p.136-143
Hauptverfasser:	Abraham, David J, Eckes, Beate, Rajkumar, Vineeth, Krieg, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Fibroblasts - pathology Fibrosis - pathology Humans Mesenchymal Stromal Cells - cytology Scleroderma, Systemic - etiology Scleroderma, Systemic - pathology Signal Transduction
Online-Zugang:	Volltext
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