The addition of a new immunomodulator with the adjuvant adaptation ADAD system using fatty acid binding proteins increases the protection against Fasciola hepatica

Fatty acid binding proteins (FABP) have shown protective immune response against Fasciola hepatica infection. We evaluated the protection induced by the Fh12 FABP from F. hepatica (Fh12) combined with the new immunomodulator the lipidic aminoalcohol OA0012 in the ADAD system in mice and sheep. In th...

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Veröffentlicht in:	Veterinary parasitology 2008-05, Vol.153 (1), p.176-181
Hauptverfasser:	López-Abán, J., Nogal-Ruiz, J.J., Vicente, B., Morrondo, P., Diez-Baños, P., Hillyer, G.V., Martínez-Fernández, A.R., Feliciano, A. San, Muro, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAD system Adjuvants, Immunologic - administration & dosage Animals Antibodies, Helminth - blood Antibodies, Helminth - immunology disease control FABP Fasciola hepatica Fasciola hepatica - immunology Fascioliasis - prevention & control Fascioliasis - veterinary fatty acid-binding proteins Fatty Acid-Binding Proteins - administration & dosage fecal egg count Female helminths immune response Immunoglobulin G - blood Immunologic Factors - administration & dosage Immunomodulator immunomodulators Lipidic aminoalcohol liver flukes Male Mice Mice, Inbred BALB C OA0012 Phlebodium Phlebodium pseudoaureum Sheep Sheep Diseases - immunology Sheep Diseases - parasitology Sheep Diseases - prevention & control Vaccine vaccine adjuvants vaccine development vaccines Vaccines - immunology
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